Cancer

is one of the most serious diseases in the developed world.
It causes 7 million deaths each year worldwide, mostly as a result of the development of secondary tumors (metastases).
Unfortunately, the generation of metastases in healthy tissue from a primary tumor is unpredictable and we still do not have an effective treatment to prevent the metastatic process.

Azelead

uses zebrafish embryos to detect the real time stages of metastatic progression:
— Loss of cell polarity
— Cell motility
— Matrix degradation
— Migration through the extracellular matrix
— Intravasation/extravasation in blood vessels and proliferation in tissue.

Based on new state-of-the-art technology, AZELEAD has identified 3 new compounds capable of preventing metastasis and cancer progression in vivo.